We can stop aging by switching off the crucial enzyme responsible for cellular senescence.
Scientific research shows that we are a step closer to a longer and healthier physical life. It looks like science is able to reverse the so far unavoidable natural aging process of cell tissue.
The Korea Advanced Institute of Science and Technology (KAIST) made this exiting news public.
KAIST scientists explained that simulations show that we can stop and reverse cellular senescence.
They investigated the enzyme called PDK1 in incubated senescent skin fibroblasts and three-dimensional skin equivalent tissue models.
The important findings by the team brings a closer look into the very complex mechanism of cellular senescence and present a potential therapeutic strategy to tackle age-related diseases associated with the accumulation of senescent cells.
Enzyme PDK1 plays a key role. This enzyme is crucial as it comes to the aging process of cells. The researchers discovered that blocking PDK1 would lead to the inhibition of two downstream signaling molecules, which in turn restore the cells’ ability to enter back into the cell cycle. Notably, the cells retained their capacity to regenerate wounded skin without proliferating in a way that could lead to malignant transformation.
Professor Kwang-Hyun about the findings: “Our research opens the door for a new generation that perceives aging as a reversible biological phenomenon”
Cells have the ability to responding to a variety of factors, such as oxidative stress, DNA damage, and shortening of the telomeres capping the ends of chromosomes, by entering a stable and persistent exit from the cell cycle.
This cellular senescence is unmissable because it prevents damaged cells from proliferating and turning into cancer cells.
On the other hand, this natural process plays a dominant part to aging and particularly age related diseases.
The research show undebatable evidence that we can reverse cellular senescence.
However, the laboratory approaches used thus far also impair tissue regeneration or have the potential to trigger malignant transformations.
The scientists recommend further investigations in organs and organisms to determine the full impact of PDK1 inhibition. Since the gene that codes for PDK1 is overexpressed in some cancers, the scientists expect that inhibiting it will have both anti-aging and anti-cancer effects.
The numbers show it over and over again, COVID-19 is no worse as a seasonal flu.
Last week, WHO figures confirmed again that the number of Corona casualties is less than in many “ordinary” flu seasons in the years gone by.
Fact: There never was a seasonal flu without hospitalizations and people dying. Elderly patients die of side effects. This is normal but nowadays considered as not normal.
Even young people can die as they suffer an underlying health condition.
And many cases, in which patients did not show any health issues before, were afterwards explained with a possible hidden condition that contributed to the fatality.
The medical service can’t cope with the current crisis. That’s true.
Not because of large demand from sick patients but the huge number of employees on sick leave. As in the past doctors and nurses with a runny nose and cough stayed at work, now they are at home in self- quarantine. This is leading to no other conclusion as the “pressure” on hospital staff is widely fabricated. ICU’s in many hospitals are empty.
It is a shame and crime that our lives are now based on a COVID lie that nobody seems to be able to stop. Is it worth it to ruin the life of many healthy people and destroy economies just to save the life of a relatively small number of old patients that also during a “normal” flu season end up in hospitals or die?
I am not a conspiracy theorist but we need not much fantasy to conclude that something dark came to this world.
The mass media don’t have the guts to ask critical questions. Why? The MSM ignore the real facts and numbers. Why is this not part of the story? On the contrary, without real facts, journalists pump up the pressure on politicians to impose even stronger restrictions and further destroy the quality of life.
Do not forget that we deal with something that is known for generations, hundreds of years and we never shied from it. We accepted that the flu was something unavoidable as a part of life.
Over the past nine months, something weird happened. Governments round the globe abused the virus quite deliberately to reduce once gutsy and stoical people to a state of terror.
It is becoming more and more provable that the Corona talk in de media is junk. Again, the “official” figures simply do not compute. We are informed about positive Corona tests not informed about real sick patients. There is no other conclusion than we are being lied to.
Corona is no pandemic, the Spanish Flu, with over 100 million casualties, was.
As future viruses are looming, the future is bleak. We are already prepared for this dark future as politicians warn us that we never will get back to normal. State terror will be in place as governments take away our freedom.
There is no other explanation as a dark agenda behind it. As more upheaval is on the horizon, Corona could be the trigger of the big tribulation as described in the Book of Revelation, The Apocalypse of John.
Figures show that the linear TV audience (traditional TV broadcasting) is fed up with the ongoing scaremongering about a virus that’s proven less fatal as the seasonal flu.
As they don’t stop bringing bad news about Corona, major TV networks round the globe are now facing a major decline in viewing rates as never seen before.
More and more people know it for sure. For a better sleep, turn off your TV.
It emerged that so far in 2020 the open network viewing rates dropped catastrophically as audiences massively turn their back to the bad news spreading mainstream media.
A media researcher explained: “It seems that viewers are getting sick and tired about project fear. They have had enough of the never-ending and often misleading information.
The Corona message on TV is dominated by a lack of critical questions in news and talk shows. There is no solid explanation to key questions”
Nationwide networks, broadcasting over the air and cable don’t refrain even a split second from keeping the COVID-19 pandemic alive. This despite a relatively low number of fatalities.
The result is that an increasing number of viewers evade the mainstream news, cut the cord and choose for streaming Video On Demand (VOD)
The worldwide traditional TV over the air and cable market (pay TV included) slowed already over the past few years in favor of video consumption through online streaming.
The Covid-19 misinformation hype is now accelerating the outflow of viewers.
The media researcher: “Viewers increasingly are aware that something is wrong. They realize that the real Corona numbers are not different compared to earlier flu outbreaks. There is no sufficient justification for the new normal”
After months of scaremongering, they now have the feeling that the severity of the virus in real life is far from bad as projected on Television. This results in higher streaming VOD churn in many markets”
In North America, operators with linear pay TV services reported a loss of more than 2 million subscribers in the first quarter of 2020 alone.
Another reason for the cord-cutting rise is that sport events are cancelled. For many sports fans a good reason to cancel their (pay-tv) packages.
There is a little spark of hope.
Although Covid-19 has dented the linear TV market, the deep loss of viewers is likely to be temporary. That’s what experts say.
When sport events resume, fans are likely to go back to their regular non-streaming TV services.
Nothing in life is what it looks like but a hospitalized American president suffering virus symptoms is something unprecedented.
For many humans, COVID-19 is no more dangerous as the seasonal flu. Not worth all the restrictions imposed on young and healthy citizens.
That doesn’t prevent some governments to use COVID-19 as a tool for deliberate destruction of economies and personal livelihood. In no time, COVID-19 became the ultimate key for governments to ruin economies and pave the way for the introduction of communism based on totalitary ruling.
That doesn’t wipe out that particularly patients above 65 years of age are extremely vulnerable.
Therefore, at the moment, it is distrustful whether the American President will survive and if, what possible damage he suffers.
CNN loves it. Donald Trump can’t do any good to the reporters working at this highly unprofessional news caster. CNN is on a hate mission. Instead of projecting an independent view, CNN produces well organized on going fabricated stories with one dark purpose only.
As America is in trouble, so is the rest of the World. What a pity for Boris Johnson now the POTUS illness drives him into the arms of the EU. No one knows in what shape the Corona suffering President will end.
Suppose he dies, it is very unlikely the UK gets a lucrative trade deal with the US.
May God forbid that we get an administration operated by Democrats. Using Donald Trump’s words : That’s not gonna happen. I hope so and pray.
But if such an unforeseen event occurs, the UK will not be treated different compared with other foreign nations.
Boris Johnson is getting very nervous and already began to behave nice and friendly towards Mrs. Ursula von der Leyen. Just in case…
Therefore the two European leaders agree that both parties, the UK and EU, should do their utmost to achieve a Brexit deal. They agree that they should agree. No more than that.
It is obvious that the UK is driven in the arms of something Boris and a majority of the Brittons don’t like.
It is an extremely sad situation as the UK is now deteriorating at exponential speed.
Should the POTUS die (even if he leaves the hospital, he is not out of the woods) or lose the November election and no UK/EU agreement is reached, the UK is doomed to become a third world country for a indefenite period of time.
These days, there is growing criticism about the way governments are handling the Corona virus.
For a large majority of the population COVID-19 is a totally harmless virus, far less severe than the seasonal flu.
Is it worth the price to sacrifice worlds economy and peoples freedom? In some countries like Cyprus, Spain and France it is. If you don’t follow the Corona rules strictly, you can end up in jail. This all with the argument that violating the rules endangers public health.
And this is not all.
Scaremongering media offer daily updates like sport event reports. Even the smallest amount of new cases is news.
Why did this not happen during earlier, even more severe, flu outbreaks? And why are emergency room operators complaining all the time as in previous years many more flu victims were treated in hospitals and many more died.
Why do officials not inform society about the real status of patients with a positive test result? Why don’t reporters ask?
In most cases, a positive test, is no evidence for real sick patients at all. Many registered patients have no or just minor complaints comparable with catching a cold.
The biggest threat might not these facts but the over exaggerated precautions to prevent attracting the virus.
The mass use of hand gels could create a so called superbug Armageddon as many other bacteria and viruses build up resistance. This is what Dr. Andrew Kemp of the University of Lincoln warns for.
Other scientists say that at this very moment, there is no evidence that alcohol based gel kills the Corona virus.
On the contrary: Recent research shows the surviving bugs which are not killed by alcohol gels are themselves highly dangerous pathogens and may increase in numbers. This implicates that in the long run our routine use of gels could cause us more harm than good.
These finding contribute to what Corona conspiracy theorists believe that most governmental Corona ruling is a hoax based on dark motives.
Shopping in the supermarket was never so dirty and dangerous as today. The massive use of decontamination gels lead to clingy, very dirty and dangerous baskets.
Maybe this is exactly what the leaders want.
Breaking the resistance of people by curfew, quarantine measures, ruining economies, taking away possessions without any legal reason, contact tracing, social distancing (a rule dated back to the USSR era to prevent demonstrations) and finally kill deliberately on the long run by creating a breeding ground for bacteria and viruses.
At the same time. future immune systems could weaken as too many precautions prevent humanity from getting necessary infections. A weakened immune system plus bacteria and viruses building up resistance is a fatal combination.